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August 1, 1977The Journal of PhysiologyOpen Access

Adaptation of the human carotid baroreceptor‐cardiac reflex.

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Population

Healthy young men

Design

Other

Authors

DEDwain L. EckbergGeneral Cardiology

Discussion

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Implication

Baroreflex adaptation may confound sustained stimulation protocols; extends animal unit data to human integrated responses but leaves open clinical implications.

Structured PICO

P
Population
Healthy young men
I
Intervention
Four intensities of neck suction applied for 5 seconds, with and without beta-adrenergic blockade
O
Outcome
Time course of decay of carotid baroreflex sinus node inhibitionsurrogate

The integrated baroreceptor-cardiac reflex in humans undergoes adaptation during sustained stimulation, following a time course similar to individual baroreceptor units in experimental animals.

Cite This Study

Dwain L. Eckberg (1977) studied this question.

synapsesocial.com/papers/6a734e00f60b59e999b86d8ahttps://doi.org/10.1113/jphysiol.1977.sp011916
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Modulation of carotid baroreflex responsiveness in man: effects of posture and propranolol1976 · 129 citations
  2. 2Comparison of the reflex heart rate response to rising and falling arterial pressure in man1972 · 161 citations
  3. 3THE EFFECTS OF AGING AND DEGENERATIVE VASCULAR DISEASE ON THE MEASUREMENT OF ARTERIAL RIGIDITY IN MAN*1961 · 53 citations
  4. 4Baroreflex inhibition of the human sinus node: importance of stimulus intensity, duration, and rate of pressure change.1977 · 97 citations
  5. 5Temporal response patterns of the human sinus node to brief carotid baroreceptor stimuli.1976 · 164 citations