Cardiac MRF using rosette trajectories for simultaneous myocardial T1, T2, and proton density fat fraction mapping

Figure 1. The designed rosette trajectory and its spectral response. (A) The rosette trajectory used in this work, where the segments used to generate images at different echo times are indicated by different colors. (B) Spectral response of the trajectory. Fat signals at −220 Hz are suppressed to 5.3%.

Figure 2. Results in the fat fraction phantom. (A) Water and fat specific T1 and T2 maps, proton density images, and the PDFF map generated by Hierarchical IDEAL using the rosette cMRF data. (B) PDFF measurements using rosette cMRF compared with reference values.

Figure 3. Representative T1 map, T2 map, water image, fat image, and PDFF maps in a healthy subject. T1 and T2 maps measured by spiral cMRF and conventional methods are shown for comparison. The field-of-view has been cropped to 150 × 150 mm2 to better visualize the heart.

Figure 4. T1 and T2 values in 16 healthy subjects measured using conventional methods, spiral cMRF, and rosette cMRF. Measurements in segment 7–12 as well as over the entire myocardium are shown. *Significant difference between spiral and rosette cMRF. †Significant difference between conventional method and spiral cMRF. ‡Significant difference between conventional method and rosette cMRF.

Figure 5. Individual PDFF over the myocardium measured using rosette cMRF in 16 healthy subjects.

Figure 6. Pre-contrast results in the first cardiomyopathy patient acquired using rosette cMRF, spiral cMRF, and conventional methods. T1 and T2 values over the entire myocardium are shown in the maps.

Figure 7. Post-contrast results in the first cardiomyopathy patient acquired using rosette cMRF, spiral cMRF, and conventional methods. T1 and T2 values over the entire myocardium are shown in the maps.

Figure 8. Pre-contrast results in the second cardiomyopathy patient acquired using rosette cMRF, spiral cMRF, and conventional methods. T1 and T2 values over the entire myocardium are shown in the maps. The field-of-view has been cropped to 150 × 150 mm2 to better visualize the heart.

Figure 9. Post-contrast results in the second cardiomyopathy patient acquired using rosette cMRF, spiral cMRF, and conventional methods. T1 and T2 values over the entire myocardium are shown in the maps. The field-of-view has been cropped to 150 × 150 mm2 to better visualize the heart.