Why the study?
Do pharmacologic neuroprotective agents prevent neurologic injury and neurocognitive dysfunction in patients undergoing cardiac surgery?
Population
Patients undergoing cardiac surgery
Comparison
Pharmacologic neuroprotective agents vs Placebo or standard care
Design
Review
Authors
Loading...
No approved neuroprotectants for cardiac surgery; leaves open a major unmet need for effective agents in future trials.
Do pharmacologic neuroprotective agents prevent neurologic injury and neurocognitive dysfunction in patients undergoing cardiac surgery?
Despite decades of research and numerous clinical trials, no pharmacologic agent has yet been proven to provide robust neuroprotection during cardiac surgery.
Hilary P. Grocott (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: