Why the study?
Do serum and urine electrolyte profiles differ between untreated mild to moderate hypertensive Nigerians and normotensive controls?
Population
40 adult Nigerians with untreated uncomplicated mild to moderate essential hypertension, and age and…
Design
Case-control
Authors
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Electrolyte differences do not guide therapy; hypothesis-generating for pathogenesis in Nigerians and needs prospective confirmation.
Do serum and urine electrolyte profiles differ between untreated mild to moderate hypertensive Nigerians and normotensive controls?
Untreated mild to moderate hypertensive Nigerians exhibit significantly higher serum sodium and chloride and lower serum potassium compared to normotensives, suggesting a potential role in the pathogenesis of hypertension in this population.
Iyalomhe et al. (2008) studied this question.
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