What question did this study set out to answer?

To determine whether potassium citrate, a nonchloride potassium salt found in fruits and vegetables, lowers blood pressure as effectively as potassium chloride in hypertensive individuals.

February 22, 2005HypertensionOpen Access

Effect of Short-Term Supplementation of Potassium Chloride and Potassium Citrate on Blood Pressure in Hypertensives

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Authors

FHFeng J. HePreventive Cardiology NMNirmala D. MarkanduGeneral / Preventive / Lipids RCR.S. ColtartKent and Canterbury Hospital

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Implication

Randomized crossover trial reveals equivalent blood pressure reduction from potassium chloride and citrate in hypertensive individuals, suggesting nonchloride dietary potassium lowers blood pressure.

Key Points

To determine whether potassium citrate, a nonchloride potassium salt found in fruits and vegetables, lowers blood pressure as effectively as potassium chloride in hypertensive individuals.
Randomized crossover trial involving N=14 hypertensive individuals.
Participants received potassium chloride (96 mmol/d) and potassium citrate (96 mmol/d) for 1 week each.
Assessed blood pressure and 24-hour urinary potassium excretion relative to baseline.
Baseline blood pressure (151±16/93±7 mm Hg) fell significantly with potassium chloride (140±12/88±7 mm Hg) and potassium citrate (138±12/88±6 mm Hg).
No significant difference was observed between potassium chloride and citrate: mean difference 1.6 mm Hg (95% CI: -2.3 to 5.6) for systolic and 0.6 mm Hg (95% CI: -2.4 to 3.7) for diastolic blood pressure.

Cite This Study

He et al. (2005) studied this question.

synapsesocial.com/papers/6a73796a427d94f6ee71ae28 https://doi.org/10.1161/01.hyp.0000158264.36590.19

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Implication

Randomized crossover trial reveals equivalent blood pressure reduction from potassium chloride and citrate in hypertensive individuals, suggesting nonchloride dietary potassium lowers blood pressure.

Effect of Short-Term Supplementation of Potassium Chloride and Potassium Citrate on Blood Pressure in Hypertensives

Discussion

Member takes

Implication

Key Points

Cite This Study

Effect of Short-Term Supplementation of Potassium Chloride and Potassium Citrate on Blood Pressure in Hypertensives

Discussion

Member takes

Implication

Key Points

Cite This Study

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