Population
In vitro model using actin-binding proteins of the intestinal brush border and skeletal muscle actomyosin…
Comparison
Addition of TW 260/240 or villin vs Control
Design
Preclinical
Authors
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Leaves open whether filament cross-linkers modulate cardiac contractility; hypothesis-generating for in vivo validation in muscle models.
Actin filament cross-linking and intermediate filament lengths enhance actomyosin ATPase activity in vitro, whereas short filament lengths inhibit it.
Coleman et al. (1985) studied this question.
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