Why the study?
In the acute phase, Takotsubo syndrome can mimic acute coronary syndrome, making their differentiation a significant clinical challenge.
Does echocardiography differentiate Takotsubo syndrome from acute myocardial infarction in patients presenting with acute coronary syndrome?
Does echocardiography differentiate Takotsubo syndrome from acute myocardial infarction in patients presenting with acute coronary syndrome?
Advanced echocardiographic techniques can help differentiate Takotsubo syndrome from acute myocardial infarction, though coronary angiography remains the gold standard for definitive diagnosis.
Symmetrical LV dysfunction on echo may aid acute TTS-ACS differentiation; leaves open prospective validation before practice change.
Reversible left ventricle dysfunction is a key feature of Takotsubo syndrome (TTS), but in the acute phase it can mimic an acute coronary syndrome, making this differentiation a significant challenge. Echocardiography is widely used in the early evaluation of these patients, and advanced imaging tools have highlighted the differences between both syndromes. The symmetrical pattern of left ventricular dysfunction, extending beyond the territory of a single coronary artery, associated with a less severe diastolic dysfunction, right ventricle involvement and a typical complete recovery of wall-motion abnormalities points towards the diagnosis of TTS. Despite all the imaging advances made so far, evaluation of coronary anatomy remains mandatory in these patients.
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Fernandes et al. (2019) studied this question.
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