Normal serum lactate dehydrogenase (LDH) levels do not definitively rule out pump thrombosis in patients with left ventricular assist devices.
Normal LDH may not exclude LVAD pump thrombosis; hypothesis-generating case that challenges LDH as sole marker and leaves open need for better diagnostics.
Left ventricular assist device (LVAD) pump thrombosis is a well-known complication of LVAD placement. Elevated lactate dehydrogenase (LDH) has classically been the first objective marker of pump thrombosis. In this case, we present a patient found to have normal serum LDH values but was ultimately found to have significant pump thrombosis.
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Shelton et al. (2016) studied this question.
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