Why the study?
Do serum biomarkers (NT-pro-BNP, cTnT, hs-CRP) accurately diagnose severe left ventricular hypertrophy and systolic dysfunction in chronic peritoneal dialysis patients?
Population
230 chronic peritoneal dialysis (PD) patients
Design
Cross-sectional
Authors
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May support ruling out severe LV issues in peritoneal dialysis; leaves open prospective validation with anuria-adjusted thresholds.
Do serum biomarkers (NT-pro-BNP, cTnT, hs-CRP) accurately diagnose severe left ventricular hypertrophy and systolic dysfunction in chronic peritoneal dialysis patients?
Serum NT-pro-BNP and cTnT are useful for excluding systolic dysfunction and severe LV hypertrophy in chronic peritoneal dialysis patients, though diagnostic cut-off thresholds must be adjusted higher in anuric patients.
Wang et al. (2009) studied this question.
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