Urine secretion by isolated Malpighian tubules of Carausius is accelerated by a diuretic hormone which can be extracted from the brain, corpora cardiaca and suboesophageal ganglion. The level of this hormone in the haemolymph varies according to the state of hydration of the insect. The hormone is inactivated by the tubules, and a mechanism is proposed whereby the tubules might be controlled by the hormone in vivo.
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Diana E. M. Pilcher (1970) studied this question.
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