Why the study?
Does escitalopram improve quality of life in patients with acute coronary syndrome and co-morbid depression?
Population
1152 patients recruited 2-14 weeks after a confirmed acute coronary syndrome episode, including 446 with…
Comparison
Escitalopram for 24 weeks vs Placebo or medical treatment only (MTO)
Design
RCT, randomized, double blind
Follow-up
1 year
Authors
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Supports treating comorbid depression with escitalopram post-ACS; extends evidence for sustained QoL gains in cardiac populations.
Does escitalopram improve quality of life in patients with acute coronary syndrome and co-morbid depression?
Treatment of co-morbid depression with escitalopram in patients with recent acute coronary syndrome significantly improves quality of life up to 1 year.
Kim et al. (2014) studied this question.
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