Evaluation of the antitumor immune response to C₆₀ fullerene

In vitro experiments have shown that C 60 fullerenes exhibit cytotoxic effects against tumor cells and modulate the cytotoxic activity of immune cells. In vivo therapeutic experiments on the model of Lewis lung carcinoma showed that C 60 fullerenes exhibit an antimetastatic effect (reduction of metastases by 27%), which is realized by activating macrophages and stimulating the synthesis of humoral factors, which significantly increase the cytotoxicity of treated animals serum.