Why the study?
Does stealth liposomal doxorubicin accumulate selectively in bone metastases compared to skeletal muscle in patients with metastatic breast carcinoma?
Population
2 women with metastatic breast carcinoma who responded to treatment with stealth liposomal doxorubicin and…
Comparison
Stealth liposomal doxorubicin vs Tumor-free adjacent skeletal muscle
Design
Case_series
Authors
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May support selective accumulation in bone metastases; hypothesis-generating and should not yet change practice.
Does stealth liposomal doxorubicin accumulate selectively in bone metastases compared to skeletal muscle in patients with metastatic breast carcinoma?
Stealth liposomal doxorubicin demonstrates selective accumulation in metastatic breast carcinoma cells within bone compared to skeletal muscle.
Symon et al. (1999) studied this question.
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