Evaluation of an Automated Executed Version of an ELISA for the Serological Diagnosis of Dengue Infections

The incidence of dengue is increasing in many countries and at the present time, around half of the world's population is at risk of infection. Dengue is an arthropod-borne virus (arbovirus) that continues to pose an important challenge to public health authorities worldwide. A critical task in managing arboviral outbreaks and epidemics is the selection of laboratory technology for timely and accurate diagnosis. In this study, we assessed the performance of the DYNEX® DS2 Automated Processing System for the diagnosis of dengue vis a vis the manually executed procedure. The levels of agreement were calculated and showed 94%, 96%, and 90% positive percent agreement, negative percent agreement, and overall percent agreement, respectively. In conclusion, both tests displayed comparable performances.