Population
Yeast two-hybrid system, in vitro binding assays, and C(2)C(12) myoblasts
Design
Preclinical
Authors
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May inform strategies for muscle wasting; leaves open translation from myoblast models to clinical use.
Titin-cap interacts with Myostatin and regulates its secretion, providing a potential mechanism for modulating skeletal muscle growth.
Nicholas et al. (2002) studied this question.
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