Why the study?
Although guidelines recommend single-pill combinations (SPCs) as first-line therapy for hypertension, availability remains limited, evidence on access is largely not specific to SPCs, and determinants of availability are dispersed across heterogeneous sources.
This protocol outlines a structured scoping review methodology to map the regulatory, economic, health system, and sociocultural determinants of antihypertensive single-pill combination availability in Sub-Saharan Africa.
Protocol for review of SPC access barriers in hypertension; leaves open policy determinants until evidence synthesis completes.
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Marcolino et al. (2026) studied this question.
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