November 1, 1999The International Journal of Artificial Organs
A Three-dimensional Analysis of Flow in the Pivot Regions of an ATS Bileaflet Valve
Population
ATS bileaflet mechanical heart valve model (computational and experimental)
Design
Preclinical
Authors
Discussion
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Member takes
Implication
May heighten thrombosis concern with bileaflet valves; leaves open clinical translation from animal models.
Structured PICO
P
Population
ATS bileaflet mechanical heart valve model (computational and experimental)
I
Intervention
Three-dimensional computational fluid dynamics (CFD) modelling combined with enlarged scale experimental modelling of forward flow
O
Outcome
Blood flow characteristics, specifically shear stresses and regions of persistent blood recirculation in the leaflet pivot regionssurrogate
CFD and experimental modeling of the ATS bileaflet valve reveals recirculating blood regions downstream of the valve that may persist longer than one cardiac cycle, potentially contributing to thrombosis risk.
Cite This Study
Kelly et al. (1999) studied this question.