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March 15, 2006Proceedings of the National Academy of SciencesOpen Access

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5α restriction factor

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Authors

MSMatthew StremlauJohns Hopkins UniversityMPMichel PerronHarvard UniversityMLMark N. LeeYale Cancer Center

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Stremlau et al. (2006) studied this question.

synapsesocial.com/papers/6a73ac9caa90adf506fb73cdhttps://doi.org/10.1073/pnas.0509996103
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Also Consider

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  1. 1Cyclophilin A is required for TRIM5α-mediated resistance to HIV-1 in Old World monkey cells2005 · 155 citations
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  3. 3TRIM5α selectively binds a restriction-sensitive retroviral capsid2005 · 241 citations
  4. 4Cytosolic Gag p24 as an Index of Productive Entry of Human Immunodeficiency Virus Type 11998 · 209 citations
  5. 5Species-Specific Tropism Determinants in the Human Immunodeficiency Virus Type 1 Capsid2004 · 121 citations