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November 1, 1977Stroke

Concomitants of atherosclerotic carotid artery stenosis.

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Population

75 patients with angiographically and surgically proven internal carotid stenosis, and age and sex matched…

Design

Case-control

Authors

GDGordon W. DuncanWestern General Hospital RLRobert S. LeesGeneral / Preventive / Lipids RORobert G. OjemannJikei University School of Medicine

Discussion

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Implication

Observational links to standard risks extend coronary parallels; leaves open whether modification prevents carotid events.

Key Points

The aim is to identify metabolic and other factors related to atherosclerotic carotid artery stenosis.
Compared 75 patients with carotid stenosis to age and sex matched control subjects.
Evaluated plasma cholesterol, triglycerides, glucose, blood pressure, smoking, and history of ischemic heart disease.
Assessed the prevalence of diabetes mellitus and peripheral vascular disease.
Patients with carotid stenosis had higher systolic and diastolic blood pressures (p<0.01).
Increased plasma cholesterol and triglyceride levels were found in stenosis patients (p<0.01).
Significantly greater likelihood of smoking and diabetes mellitus was observed in carotid stenosis patients.

Structured PICO

P

Population

75 patients with angiographically and surgically proven internal carotid stenosis, and age and sex matched control subjects

C

Comparator

Age and sex matched control subjects

O

Outcome

Differences in metabolic and clinical risk factors including plasma cholesterol, triglycerides, glucose, blood pressure, cigarette smoking, ischemic heart disease, peripheral vascular disease, and family history

The risk factors for carotid stenosis are similar to those for coronary atherosclerosis, suggesting that risk factor modification may help prevent cerebrovascular disease.

Cite This Study

Duncan et al. (1977) studied this question.

synapsesocial.com/papers/6a73b136ef8a0d4f3a4c9ff9 https://doi.org/10.1161/01.str.8.6.665

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