Bacillus thuringiensis Cry1Ab: A functional core of transgenic maize

This is the authors' abstract. We don't add key points for this paper.

Transgenic maize expressing insecticidal proteins from Bacillus thuringiensis (Bt), primarily Cry proteins, has become a cornerstone of Integrated Pest Management strategies against major lepidopteran pests. In China, Cry1Ab remains the predominant Bt protein expressed in most commercialized maize varieties. In this review, we summarize: 1) the research, development, and adoption of Cry1Ab; 2) its structure and insecticidal spectrum; and 3) its mode of action. We conclude by discussing the evolution of insect resistance to Cry1Ab and the corresponding resistance management strategies.