Why the study?
Does pharmacological stimulation of peripheral arterial chemoreceptors by i.v. injection of almitrine bismesylate alter cortical and medullary blood flows in conscious rats?
Population
conscious rats
Comparison
pharmacological stimulation of peripheral… vs baseline (before stimulation)
Design
Preclinical
Authors
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Does not inform clinical practice; leaves open chemoreceptor modulation of regional renal perfusion for human studies.
Does pharmacological stimulation of peripheral arterial chemoreceptors by i.v. injection of almitrine bismesylate alter cortical and medullary blood flows in conscious rats?
Pharmacological stimulation of arterial chemoreceptors differentially affects renal blood flow, reducing cortical flow in innervated kidneys without altering medullary flow.
Ledderhos et al. (1998) studied this question.
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