Eligibility in Cancer Clinical Research: The Intersection of Discovery, Generalizability, Beneficence, and Justice

This is the authors' abstract. We don't add key points for this paper.

Eligibility criteria in clinical trials limit the study population for safety and scientific purposes. The American Society of Clinical Oncology and The Friends of Cancer Research collaboration reconsidered common eligibility criteria in cancer trials and found many to be unnecessarily restrictive. The current recommendations further their efforts to facilitate accrual and improve the generalizability of research results to practice. See related articles, p. 2394, 2400, 2408, 2416, 2424, and 2430