Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 1998Acta Physiologica ScandinavicaOpen Access

Severe haemorrhage partially reverses moderate haemorrhage‐induced decrease in intestinal vascular capacitance

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does severe haemorrhage compared to moderate haemorrhage alter intestinal vascular capacitance in an anaesthetized pig model?

Population

12 chloralose-anaesthetized pigs (6 of which were vagotomized prior to induction of haemorrhage)

Comparison

Severe haemorrhage vs Moderate haemorrhage

Design

Preclinical

Authors

WWangJikei University School of MedicineWWELTRRUTLEN

Discussion

Loading...

Member takes

Implication

Preclinical findings only; leaves open vagal modulation of intestinal capacitance during progressive hemorrhage.

Structured PICO

Does severe haemorrhage compared to moderate haemorrhage alter intestinal vascular capacitance in an anaesthetized pig model?

P
Population
12 chloralose-anaesthetized pigs (6 of which were vagotomized prior to induction of haemorrhage)
I
Intervention
Severe haemorrhage (removal of 25% of blood volume)
C
Comparator
Moderate haemorrhage (removal of 15% of blood volume)
O
Outcome
Intestinal vascular capacitance (portal vein pressure/intestinal blood volume relationship)surrogate

Severe haemorrhage partially reverses the moderate haemorrhage-induced decrease in intestinal vascular capacitance, an effect mediated in part by the cardiac vagal reflex.

Cite This Study

Wang et al. (1998) studied this question.

synapsesocial.com/papers/6a73bf71d0d1650e4d69f09ahttps://doi.org/10.1046/j.1365-201x.1998.0268f.x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Changes in regional vascular capacitance during prostacyclin-induced cardiac vagal reflex in pigs1994 · 5 citations
  2. 2The Role of Vagal Cardiac Nerves and Arterial Baroreceptors in the Circulatory Adjustments to Hemorrhage in the Cat1970 · 125 citations
  3. 3Reflex control of mesenteric vein diameter and pressure in situ in rabbits1989 · 14 citations
  4. 4Hemodynamic effects of hemorrhage and subsequent naloxone treatment in conscious rabbits1984 · 43 citations
  5. 5Radionuclide assessment of peripheral intravascular capacity: a technique to measure intravascular volume changes in the capacitance circulation in man.1981 · 168 citations