Key result
Intracoronary prostacyclin infusion increases intestinal blood volume ~7% via cardiac vagal reflex, lowering LVEDP.
p-value: p=< 0.01
Intracoronary prostacyclin infusion increases intestinal blood volume via an active change in vascular capacitance mediated by a cardiac vagal reflex.
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Findings limited to animal models; leaves open whether cardiac vagal reflexes modulate intestinal capacitance in humans.
Wang et al. (1994) studied this question. Prostacyclin (PGI2) was evaluated on Intestinal blood volume (p=< 0.01). Intracoronary prostacyclin infusion increased intestinal blood volume by 7.0% (P < 0.01) via a cardiac vagal reflex, accompanied by decreases in liver blood volume and left ventricular end-diastolic pressure.
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