Why the study?
Does improved metabolic control enable eutrophic remodeling of small arteries in response to increased blood pressure in patients with type 1 diabetes mellitus?
Does improved metabolic control enable eutrophic remodeling of small arteries in response to increased blood pressure in patients with type 1 diabetes mellitus?
In patients with type 1 diabetes mellitus, metabolic improvements enable small arteries to undergo eutrophic rather than hypertrophic remodeling in response to increased blood pressure.
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Metabolic control may favor eutrophic remodeling in hypertensive T1DM; hypothesis-generating and requires prospective trials before practice implications.
Greenstein et al. (2009) studied this question.
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