Arterial thromboembolism in patients with sick sinus syndrome: prediction from pacing mode, atrial fibrillation, and echocardiographic findings
Why the study?
Does single chamber atrial pacing reduce arterial thromboembolism compared to ventricular pacing in patients with sick sinus syndrome?
Population
225 patients with sick sinus syndrome, divided into subgroups with and without brady-tachy syndrome at time…
Comparison
Single chamber atrial pacing vs Single chamber ventricular pacing
Design
RCT, randomised to single chamber atrial or ventricular pacing
Authors
Discussion
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Member takes
Implication
Favors atrial over ventricular pacing to lower thromboembolism risk in sick sinus syndrome; confirms benefit especially with brady-tachy syndrome.
Structured PICO
Does single chamber atrial pacing reduce arterial thromboembolism compared to ventricular pacing in patients with sick sinus syndrome?
P
Population
225 patients with sick sinus syndrome, divided into subgroups with and without brady-tachy syndrome at time of randomisation.
I
Intervention
Single chamber atrial pacing
C
Comparator
Single chamber ventricular pacing
O
Outcome
Occurrence of arterial thromboembolism during follow uphard clinical
In patients with sick sinus syndrome, arterial thromboembolism is associated primarily with brady-tachy syndrome and ventricular pacing, with the lowest risk seen in atrial paced patients without atrial fibrillation.
Cite This Study
Andersen et al. (1999) studied this question.