Why the study?
Does catheter-directed neodymium:YAG laser injury produce controlled myocardial lesions without adverse hemodynamic or proarrhythmic effects in a canine model?
Population
Canine model (in vitro and in vivo)
Design
Preclinical
Authors
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Feasibility of controlled laser myocardial injury without acute complications shown in canines; leaves open translation to human ventricular arrhythmia ablation.
Does catheter-directed neodymium:YAG laser injury produce controlled myocardial lesions without adverse hemodynamic or proarrhythmic effects in a canine model?
Catheter-directed neodymium:YAG laser injury can produce controlled left ventricular myocardial lesions in a canine model without acute adverse hemodynamic or proarrhythmic effects, supporting its potential for ventricular arrhythmia ablation.
Vincent et al. (1989) studied this question.
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