Why the study?
Does permanent pacemaker implantation reduce the recurrence of syncope in patients with cardioinhibitory vasovagal syncope?
Does permanent pacemaker implantation reduce the recurrence of syncope in patients with cardioinhibitory vasovagal syncope?
Permanent pacemaker implantation may be beneficial for a highly selected subset of older patients with recurrent, severe cardioinhibitory vasovagal syncope and documented asystole, despite mixed results in double-blind trials.
Pacemaker may reduce recurrence in selected cardioinhibitory cases with asystole; leaves open optimal patient selection and long-term benefit.
The most frequent cause of syncope is vasovagal reflex. It is associated with worse quality of life, depression, fatigue and physical injury. Recurrence of vasovagal syncope is an aggravating, reaching the rate of 69%. Initial step and pharmacological treatment may not work, especially in patients with recurrent syncope without prodrome. These patients can present cardioinhibitory response with asystole. Studies were designed to analyses the effectiveness of pacemaker for prevention of syncope. In this review, nonrandomized clinical trials, open-label randomized, double-blind randomized, placebo-controlled, and studies based on tilt test or Implantable Loop Recorder findings will be discussed.
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Rose Mary Ferreira Lisboa da Silva (2016) studied this question.
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