Why the study?
Does beta-blocker therapy improve clinical symptoms in patients with atrial fibrillation associated with cardiomyopathy and hyperthyroidism?
Does beta-blocker therapy improve clinical symptoms in patients with atrial fibrillation associated with cardiomyopathy and hyperthyroidism?
Beta-blocker therapy may be effective for improving clinical symptoms in patients with atrial fibrillation associated with cardiomyopathy and hyperthyroidism.
May relieve symptoms in hyperthyroid AF cardiomyopathy after thyroid normalization; hypothesis-generating case report requiring confirmation.
We report a case of dilated cardiomyopathy with hyperthyroidism. A 28-year-old man was admitted because of congestive heart failure and atrial fibrillation, and was newly diagnosed as having hyperthyroidism. Despite administration of antithyroid medication, he developed recurrent congestive heart failure. An echocardiogram revealed a moderately dilated left ventricle with diffuse hypokinesis. Though his thyroid function normalized, the patient's cardiac dysfunction did not improve. Beta-blocker therapy was begun with subsequent improvement in clinical symptoms. This suggests that beta-blocker treatment may be effective in patients with atrial fibrillation associated with cardiomyopathy and hyperthyroidism.
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Watanabe et al. (1995) studied this question.
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