• Introduction • Lipid rafts and caveolae • Caveolin gene family • Polymerase I and transcript release factor (PTRF) • Cholesterol • Signal transduction • G-protein coupled receptors • ENOS • Caveolae and disease • Prion diseases • Tumourigenesis • Animal models • Future direction Studies on the structure and function of caveolae have revealed how this versatile subcellular organelle can influence numerous signalling pathways. This brief review will discuss a few of the key features of caveolae as it relates to signalling and disease processes.
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Thomas et al. (2008) studied this question.
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