Implantable Cardioverter-Defibrillators for Primary Prevention in Patients With Ischemic or Nonischemic Cardiomyopathy

Letters6 February 2018Implantable Cardioverter-Defibrillators for Primary Prevention in Patients With Ischemic or Nonischemic CardiomyopathyLaszlo Littmann, MD, PhDLaszlo Littmann, MD, PhDCarolinas Medical Center, Charlotte, North Carolina (L.L.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L17-0691 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:I read Kołodziejczak and colleagues' review with interest (1). European and U.S. guidelines assign a class I recommendation for prophylactic implantable cardioverter-defibrillator (ICD) therapy in patients with systolic heart failure, but a study of patients with nonischemic cardiomyopathy (DANISH [Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality]) did not show mortality benefit from this intervention (2). In response, Kołodziejczak and colleagues performed a meta-analysis of prophylactic ICD trials (1). They reported that prophylactic ICDs significantly reduced all-cause mortality, supporting use of this intervention in patients with ischemic or ...References1. Kołodziejczak M, Andreotti F, Kowalewski M, Buffon A, Ciccone MM, Parati G, et al. Implantable cardioverter-defibrillators for primary prevention in patients with ischemic or nonischemic cardiomyopathy: a systematic review and meta-analysis. Ann Intern Med. 2017;167:103-11. [PMID: 28632280]. doi:10.7326/M17-0120 LinkGoogle Scholar2. Køber L, Thune JJ, Nielsen JC, Haarbo J, Videbæk L, Korup E, et al; DANISH Investigators. Defibrillator implantation in patients with nonischemic systolic heart failure. N Engl J Med. 2016;375:1221-30. [PMID: 27571011] doi:10.1056/NEJMoa1608029 CrossrefMedlineGoogle Scholar3. Bardy GH, Lee KL, Mark DB, Poole JE, Packer DL, Boineau R, et al; Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med. 2005;352:225-37. [PMID: 15659722] CrossrefMedlineGoogle Scholar4. Poole JE, Johnson GW, Hellkamp AS, Anderson J, Callans DJ, Raitt MH, et al. Prognostic importance of defibrillator shocks in patients with heart failure. N Engl J Med. 2008;359:1009-17. [PMID: 18768944] doi:10.1056/NEJMoa071098 CrossrefMedlineGoogle Scholar5. Shen L, Jhund PS, Petrie MC, Claggett BL, Barlera S, Cleland JGF, et al. Declining risk of sudden death in heart failure. N Engl J Med. 2017;377:41-51. [PMID: 28679089] doi:10.1056/NEJMoa1609758 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Carolinas Medical Center, Charlotte, North Carolina (L.L.)Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L17-0691. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoImplantable Cardioverter-Defibrillators for Primary Prevention in Patients With Ischemic or Nonischemic Cardiomyopathy Michalina Kołodziejczak , Felicita Andreotti , Mariusz Kowalewski , Antonino Buffon , Marco Matteo Ciccone , Gianfranco Parati , Pietro Scicchitano , Julia M. Umińska , Stefano De Servi , Kevin P. Bliden , Jacek Kubica , Alessandro Bortone , Filippo Crea , Paul Gurbel , and Eliano P. Navarese Implantable Cardioverter-Defibrillators for Primary Prevention in Patients With Ischemic or Nonischemic Cardiomyopathy Michalina Kołodziejczak , Felicita Andreotti , and Eliano Pio Navarese Implantable Cardioverter-Defibrillators for Primary Prevention in Patients With Ischemic or Nonischemic Cardiomyopathy Rahman Shah Metrics 6 February 2018Volume 168, Issue 3Page: 233KeywordsCardiomyopathiesDisclosureHeart failureImplantable cardioverter defibrillatorsLongitudinal studiesMortalityRandomized trialsShockSudden cardiac deathTreatment guidelines ePublished: 6 February 2018 Issue Published: 6 February 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...