Why the study?
Does sleep alter blood pressure, heart rate, and neurohormonal correlates in patients with uncomplicated essential hypertension?
Does sleep alter blood pressure, heart rate, and neurohormonal correlates in patients with uncomplicated essential hypertension?
Sleep induces significant hemodynamic and neurohormonal shifts in patients with essential hypertension, characterized by decreased blood pressure and sympathetic tone but increased renin-angiotensin activity.
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Nocturnal BP and sympathetic declines with rising renin-angiotensin activity in hypertension are hypothesis-generating; prospective studies needed before clinical consideration.
Leeuw et al. (1985) studied this question.