Objectives: To definite antibiotic-resistant phenotypes of Klebssiella pneumoniae isolated; Identifying some virulence genes and antibiotic resistance genes in strains of Klebssiella pneumoniae isolated from clinical samples collected in infected patients. Methods: We cultured, isolated and identified Klebsiella pneumoniae. Then we definitely the sensitivity to antibiotics of bacteria by disk diffusion (Kirby-Bauer) method, definited the production of ESBL. Considering the proportion of blaNDM-1, blaKPC, blaOXA-48, magA, rmpA genes by multiplex PCR. Results: Klebssiella pneumoniae isolates were resistant to antibiotics with high proportion. All 43 isolates of Klebssiella pneumoniae with ESBL (+) had higher proportion of antibiotic resistance than ESBL (-) isolates. Klebssiella pneumoniae carried antibiotic resistance genes blaNDM-1, blaKPC, blaOXA-48 were 11%, 2%, 2%. There were 24% isolates of Klebssiella pneumoniae carring virulence genes rmpA, 9% of them carring magA gene. Conclusions: Klebssiella pneumoniae is highly resistant to many antibiotics. Especially Klebssiella pneumoniae isolates ESBL (+). The proportion of Klebssiella pneumoniae carrying the antibiotic resistance blaNDM-1, blaKPC, blaOXA-48 genes were 11%, 2%, 2%. The proportion of carrying the virulence magA, rmpA genes is 24% and 9%.
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Tuyet et al. (2021) studied this question.
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