February 7, 2014Circulation Cardiovascular Imaging
Decision Making in Asymptomatic Aortic Regurgitation in the Era of Guidelines
Why the study?
Do resting LV/RV strain and exercise TAPSE predict the need for valve surgery in patients with asymptomatic aortic regurgitation?
Population
159 consecutive patients with isolated moderately severe to severe asymptomatic aortic regurgitation and…
Design
Cohort
Follow-up
30±21 months
Authors
Discussion
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Member takes
Implication
May refine surgical timing decisions in asymptomatic AR; extends echocardiographic markers but remains hypothesis-generating.
Structured PICO
Do resting LV/RV strain and exercise TAPSE predict the need for valve surgery in patients with asymptomatic aortic regurgitation?
P
Population
159 consecutive patients with isolated moderately severe to severe asymptomatic aortic regurgitation and preserved left ventricular function (LVEF >50%, LVEDD ≤70 mm, LVESD ≤50 mm or ≤25 mm/m2), mean age 50±15 years, 80% male.
I
Intervention
Comprehensive resting and exercise echocardiography (including resting LV/RV strain and exercise TAPSE)
O
Outcome
Need for aortic valve surgeryhard clinical
Resting LV and RV strain, along with exercise TAPSE, provide incremental prognostic value over clinical data for predicting the need for earlier aortic valve surgery in asymptomatic aortic regurgitation.
Cite This Study
Kusunose et al. (2014) studied this question.