Under pressure, the nitro-aldol reaction of (S)-N,N-dibenzylphenylalaninal and related compounds with nitroalkanes was highly stereoselective (see scheme; R1, R2 = Me, H; R = Ph, Me, iPr, iBu). This reaction is very convenient, as it only requires high pressure and no catalyst.
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Misumi et al. (2002) studied this question.
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