High-Resolution MRI of Carotid Plaque With a Neurovascular Coil and Contrast-Enhanced MR Angiography: One-Stop Shopping for the Comprehensive Assessment of Carotid Atherosclerosis

Stefano Tartari; Roberto Rizzati; Riccardo Righi; Anna Deledda; Katia Capello; Riccardo Soverini; Giorgio Benea

doi:10.2214/ajr.10.4751

April 21, 2011American Journal of Roentgenology

High-Resolution MRI of Carotid Plaque With a Neurovascular Coil and Contrast-Enhanced MR Angiography: One-Stop Shopping for the Comprehensive Assessment of Carotid Atherosclerosis

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Why the study?

Does high-resolution MRI with a neurovascular coil and CE-MRA accurately characterize carotid plaque compared to surgical specimens in patients with carotid atherosclerosis?

Structured PICO

Does high-resolution MRI with a neurovascular coil and CE-MRA accurately characterize carotid plaque compared to surgical specimens in patients with carotid atherosclerosis?

P

Population

32 consecutive patients with 34 carotid artery stenoses

I

Intervention

High-resolution MRI on a 1.5-T unit with a neurovascular coil, including diffusion-weighted, fat-suppressed T1-weighted, contrast-enhanced MR angiography (CE-MRA), and T1-weighted 3D high-resolution sequences

C

Comparator

Surgical specimens (reference standard)

O

Outcome

Accuracy of high-resolution MRI in carotid plaque characterization (sensitivity, specificity, PPV, NPV for identifying plaque type and vulnerable features)surrogate

High-resolution MRI with a neurovascular coil and CE-MRA is highly accurate in identifying major features of vulnerable carotid plaques, such as lipid-necrotic cores, compared to surgical specimens.

Implication

Supports histologic validation of MRI for carotid plaque; leaves open impact on revascularization decisions.

Discussion

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Cite This Study

Tartari et al. (2011) studied this question.

synapsesocial.com/papers/6a73f6b70375516f85f167f4 https://doi.org/10.2214/ajr.10.4751

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High-Resolution MRI of Carotid Plaque With a Neurovascular Coil and Contrast-Enhanced MR Angiography: One-Stop Shopping for the Comprehensive Assessment of Carotid Atherosclerosis

Structured PICO

Implication

Discussion

Cite This Study

High-Resolution MRI of Carotid Plaque With a Neurovascular Coil and Contrast-Enhanced MR Angiography: One-Stop Shopping for the Comprehensive Assessment of Carotid Atherosclerosis

Structured PICO

Implication

Discussion

Cite This Study

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