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April 1, 2020Diabetes Obesity and Metabolism

Chronic kidney disease in type 2 diabetes: Implications for managing glycaemic control, cardiovascular and renal risk

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Why the study?

This review was conducted to examine the current literature on diabetes-related kidney disease and optimal cardio-renal risk management following recent outcome trials and updated international guidelines.

Design

Review

Authors

JSJeffrey W. StephensSwansea Bay University Health BoardKBKaren BrownEvergreen Health Medical CenterTMThinzar MinSwansea Bay University Health Board

Discussion

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Overview

Supports RAS blockade for DKD progression; leaves open optimal integration with newer cardio-renal therapies.

Structured PICO

P
Population
Patients with type 2 diabetes mellitus and diabetes-related kidney disease (DKD)
I
Intervention
Management strategies including renin-angiotensin system blockade, sodium-glucose cotransporter-2 inhibitors (SGLT2i), and novel steroidal mineralocorticoid receptor antagonists

SGLT2 inhibitors and renin-angiotensin system blockade are key therapies for reducing the progression of kidney disease and cardiovascular risk in patients with type 2 diabetes.

Cite This Study

Stephens et al. (2020) studied this question.

synapsesocial.com/papers/6a73f6fed5cfe862edf161fehttps://doi.org/10.1111/dom.13942
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diabetes: how to manage chronic kidney disease2022 · 1 citations
  2. 2Advancements in Pharmacotherapy for Diabetic Kidney Disease: A Systematic Review2025 · 7 citations
  3. 3Combination Pharmacotherapy in Type 2 Diabetes and Chronic Kidney Disease: Translating Evidence into Clinical Practice.2026
  4. 4Management Strategies for the Prevention and Treatment of Chronic Kidney Disease in Patients with Type 2 Diabetes2023
  5. 5Targeting kidney disease in type 1 diabetes: progress and promise2026