High-sensitivity troponin assays enable earlier MI diagnosis but require serial testing and careful clinical correlation to maintain specificity.
Answers are grounded in this paper and cite their sources.
Requires serial testing and clinical context for hs-troponin use; leaves open assay-specific standardization in practice.
New high-sensitivity troponin assays will reduce the threshold for the diagnosis of myocardial infarction (MI), as specified in the 2012 third Universal Definition of MI. They will also allow earlier diagnosis of MI, but serial testing is required for adequate specificity. They convey prognostic information in both MI and in other acute conditions. Interpretation of troponin results must be in combination with a full assessment of the clinical context. This review discusses these concepts and developments in this area.
No takes yet. Share an insight, caveat, or question.
A 2013 study studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: