Rotavirus RNA can be detected in the CSF of children with CNS symptoms and gastroenteritis, with strains matching those circulating in the community.
Warrants considering rotavirus in pediatric CNS symptoms with gastroenteritis; leaves open whether common G1P[8] strains cause direct neuroinvasion.
Rotavirus RNA was detected in the cerebrospinal fluid (CSF) of a child with central nervous system disease symptoms associated with rotavirus gastroenteritis. The rotavirus isolates from the fecal and CSF samples were genotyped as G1P[8]. Sequence analysis of the VP7 and VP4 proteins derived from the fecal and CSF samples were remarkably similar to each other and to G1P[8] rotavirus strains commonly circulating in the community and associated with gastroenteritis.
No takes yet. Share an insight, caveat, or question.
Iturriza‐Gómara et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: