Why the study?
Herbal remedies for myocardial infarction have become effective, secure, and readily accessible, prompting an examination of medicinal plants and phytochemicals to assess their potential contribution to treatment development.
What medicinal plants and phytochemicals have been used to treat myocardial infarction?
What medicinal plants and phytochemicals have been used to treat myocardial infarction?
This systematic review identifies 140 medicinal plants and their phytochemical components, predominantly flavonoids, used in the treatment of myocardial infarction, providing a basis for future herbal MI treatments.
Supports further preclinical study of flavonoid-rich plants in MI; leaves clinical adoption open pending RCTs.
BACKGROUND: Myocardial infarction (MI), also referred to as a "heart attack," is brought on by a partial or total interruption of blood supply to the myocardium. Myocardial infarction can be "silent," go undiagnosed, or it can be a catastrophic occurrence that results in hemodynamic decline and untimely death. In recent years, herbal remedies for MI have become effective, secure, and readily accessible. OBJECTIVE: The purpose of this review was to examine the medicinal plants and phytochemicals that have been used to treat MI in order to assess the potential contribution of natural substances to the development of herbal MI treatments. METHODOLOGY: A literature search was employed to find information utilizing electronic databases, such as Web of Science, Google Scholar, PubMed, Sci Finder, Reaxys, and Cochrane. RESULTS: The identification of 140 plants from 12 families led to the abstraction of data on the plant families, parts of the plant employed, chemical contents, extracts, model used, and dose. CONCLUSION: The majority of the MI plants, according to the data, belonged to the Fabaceae (11%) and Asteraceae (9%) families, and the most prevalent natural components in plants with MI were flavonoids (43%), glucosides (25%), alkaloids (23%), phenolic acid (19%), saponins (15%), and tannins (12%).
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Rathore et al. (2024) studied this question.
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