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Production of L-DOPA by the activity of tyrosinase from a strain of Aspergillus terreus 104 was investigated. Effects of substrate (L-tyrosine) concentrations, its mode of feeding to the assay mixture and also the effects of L-ascorbic acid and other antioxidants on the production rate of L-DOPA were studied. The parameters for optimal production of L-DOPA with a maximum conversion of 85% of 0.1% L-tyrosine were determined.
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Chattopadhyay et al. (1990) studied this question.
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