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August 16, 1994Proceedings of the National Academy of SciencesOpen Access

The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis.

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Authors

MNM. Marek NagiecBroad InstituteJBJulie BaltisbergerEastern Kentucky UniversityGWGerald B. WellsMarkey Cancer Center

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Nagiec et al. (1994) studied this question.

synapsesocial.com/papers/6a741b2bfb11774a0060393chttps://doi.org/10.1073/pnas.91.17.7899
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The isolation and characterization of a mutant strain of Saccharomyces cerevisiae that requires a long chain base for growth and for synthesis of phosphosphingolipids.1983 · 120 citations
  2. 2The nucleotide sequence of the HEM1 gene and evidence for a precursor form of the mitochondrial 5-aminolevulinate synthase in Saccharomyces cerevisiae1986 · 63 citations