The mercury project: A self-cleaving DNAzyme that “switches on” in the presence of Hg2+ has been revealed by in vitro selection. The enzyme 10-13 (see picture) utilizes two modified nucleobases to confer an RNaseA-like catalytic activity that requires only Hg2+ and no other divalent metal cofactor. This DNAzyme is highly selective for mercuric cations.
No takes yet. Share an insight, caveat, or question.
Hollenstein et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: