What question did this study set out to answer?

To determine the incidence, anatomical sites, risk factors, and clinical complications of nosocomial infections in hospitalized trauma patients.

November 1, 1999

Infection in Hospitalized Trauma Patients: Incidence, Risk Factors, and Complications

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Authors

GPGiuseppe PapiaSunnybrook Health Science Centre BMBarry A. McLellanSunnybrook Health Science Centre PEPhilippe El‐HelouMcMaster University

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Implication

Prospective cohort study identifies high infection rates and clinical risk factors in hospitalized trauma patients, highlighting targets for early preventive intervention.

Key Points

To determine the incidence, anatomical sites, risk factors, and clinical complications of nosocomial infections in hospitalized trauma patients.
Conducted prospective surveillance of nosocomial infections among all trauma patients admitted for more than 24 hours to a tertiary-care regional trauma center over a 1-year period (N=563).
Assessed demographic variables, injury types, clinical interventions, infection locations, severe complications, and independent risk factors using multivariate analysis.
Among 563 patients, 37% (n=209) developed a total of 367 infections (32.1 per 1,000 patient-days), most frequently affecting the lower respiratory tract (28%), urinary tract (24%), and surgical wounds (18%).
Infections were complicated by septic shock in 10% of cases (n=36), acute respiratory distress syndrome in 9% (n=32), multiorgan failure in 4% (n=13), and attributable death in 4 patients.
Multivariate analysis revealed independent infection risk with mechanical ventilation (OR = 2.6, p < 0.001), multiple surgeries (OR = 2.8, p = 0.02), multiple blood transfusions (OR = 2.3, p = 0.04), and spinal cord injury (OR = 5.0, p = 0.002), whereas initial surgery within 24 hours was protective (OR = 0.4, p = 0.001).

Cite This Study

Papia et al. (1999) studied this question.

synapsesocial.com/papers/6a742e597be5820ec40a5020 https://doi.org/10.1097/00005373-199911000-00018

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Implication

Prospective cohort study identifies high infection rates and clinical risk factors in hospitalized trauma patients, highlighting targets for early preventive intervention.

Infection in Hospitalized Trauma Patients: Incidence, Risk Factors, and Complications

Discussion

Member takes

Implication

Key Points

Cite This Study

Infection in Hospitalized Trauma Patients: Incidence, Risk Factors, and Complications

Discussion

Member takes

Implication

Key Points

Cite This Study

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