What question did this study set out to answer?

To assess the feasibility and impact of point-of-care blood glucose calibration on continuous glucose monitor accuracy in critically ill ICU patients receiving intravenous insulin.

July 5, 2025CHEST Critical CareOpen Access

The Role of Calibration Practices in Optimizing Continuous Glucose Monitor Accuracy in Critically Ill Patients

View Full Paper

Ask AI

Bookmark

Authors

MRMelanie Natasha RayanThe Ohio State University Wexner Medical Center EFEileen R. FauldsThe Ohio State University Wexner Medical Center BLBrooke LeeCenter for Inquiry

Discussion

Member takes

Implication

Feasibility study demonstrates that point-of-care calibration improves continuous glucose monitor accuracy in critically ill patients, indicating its viability for intensive care protocols.

Key Points

To assess the feasibility and impact of point-of-care blood glucose calibration on continuous glucose monitor accuracy in critically ill ICU patients receiving intravenous insulin.
Pooled data from a retrospective COVID-19 ICU study and a prospective single-arm ICU clinical trial evaluating N=110 patients receiving intravenous insulin.
Used a hybrid monitoring protocol with factory-calibrated Dexcom G6 continuous glucose monitors, requiring validation within ±20% for point-of-care blood glucose ≥100 mg/dL or ±20 mg/dL for <100 mg/dL.
Performed calibration at nurse discretion in the retrospective cohort and after persistent validation failure in the prospective trial.
A total of 55 patients (50%) received 167 calibrations, achieving validation rates of 72.6% at 6 hours, 66.7% at 12 hours, and 77.8% at 24 hours post-calibration.
Mean absolute relative difference was 25% at calibration and improved to 9.6% at 6 hours, 12.7% at 12 hours, and 13.2% at 24 hours.
Calibrations occurred within 5 minutes of point-of-care checks in 70% of instances and within 10 minutes in 83%, with no significant accuracy differences linked to calibration timing or sensor rate of change.

Cite This Study

Rayan et al. (2025) studied this question.

synapsesocial.com/papers/6a7430f70492b5dbbe989581 https://doi.org/10.1016/j.chstcc.2025.100193

View Full Paper

Ask AI

Bookmark

Implication

Feasibility study demonstrates that point-of-care calibration improves continuous glucose monitor accuracy in critically ill patients, indicating its viability for intensive care protocols.

The Role of Calibration Practices in Optimizing Continuous Glucose Monitor Accuracy in Critically Ill Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

The Role of Calibration Practices in Optimizing Continuous Glucose Monitor Accuracy in Critically Ill Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider