Case report reveals FAPI uptake in a sacral fracture, indicating an imaging pitfall in renal cancer evaluation.
We report a 77-year-old woman with papillary renal cell carcinoma showing no increased [68Ga]Ga-FAPI uptake in the primary tumor, while intense sacral FAPI uptake mimicked bone metastasis. MRI findings and 2-year follow-up supported a sacral insufficiency fracture without metastatic disease. This case highlights fracture-related FAPI uptake as an important oncologic imaging pitfall.
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Yerdeş et al. (2026) studied this question.
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