Efficient carbonyl insertion into CO and CN bonds using [Lewis acid]+[Co(CO)4]− complexes 1 and 2 gives regio- and stereoselective carbonylation of a variety of epoxides and aziridines to yield β-lactones and β-lactams, respectively. Both transformations are proposed to occur by the same mechanism, yielding products with inversion of configuration at the site of CO insertion.
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Mahadevan et al. (2002) studied this question.
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