Safety of Remdesivir in Patients With Acute Kidney Injury or CKD

Patients with chronic kidney disease (CKD), especially those with end-stage renal disease (ESRD), are susceptible to the development of severe coronavirus disease 2019 (COVID-19), which is associated with high mortality.1 Apart from respiratory support depending upon the severity of the respiratory involvement, management of COVID-19 is largely supportive. Remdesivir is a nucleotide analog that inhibits viral RNA-dependent RNA polymerase (RdRp) and that was issued an emergency use authorization by the U.S.