What question did this study set out to answer?

To determine the content and intracellular distribution of ATP in cow adrenal medulla.

December 1, 1956Acta Physiologica Scandinavica

Content and Intracellular Distribution of Adenosine Triphosphate in Cow Adrenal Medulla1

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Authors

BFB. FalckUppsala University NHNils‐Åke HillarpStatistics Sweden BHB. HögbergUppsala University

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Implication

This experiment quantifies ATP content in cow adrenal medulla, highlighting its localization in granules containing sympathomimetic amines, suggesting stability of ATP.

Key Points

To determine the content and intracellular distribution of ATP in cow adrenal medulla.
Conducted nine experiments using ion exchange chromatography to analyze acid-soluble phosphorus compounds in the cow adrenal medulla.
Measured ATP content and distribution in granules containing sympathomimetic amines.
Average ATP content was found to be 505 mg per 100 g wet weight, estimated real content at about 700 mg/100 g.
ATP is the main phosphate ester in the medulla, with ADP making up to 20% of ATP and minimal AMP present.
ATP in medullary granules remains remarkably stable and is not significantly released or degraded over 72 hours at +4 C.

Cite This Study

Falck et al. (1956) studied this question.

synapsesocial.com/papers/6a7450cefd85dc91840905b4 https://doi.org/10.1111/j.1748-1716.1956.tb01332.x

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Implication

This experiment quantifies ATP content in cow adrenal medulla, highlighting its localization in granules containing sympathomimetic amines, suggesting stability of ATP.

Content and Intracellular Distribution of Adenosine Triphosphate in Cow Adrenal Medulla1

Discussion

Member takes

Implication

Key Points

Cite This Study

Content and Intracellular Distribution of Adenosine Triphosphate in Cow Adrenal Medulla1

Discussion

Member takes

Implication

Key Points

Cite This Study

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