Key result
Noonan syndrome frequently presents with pulmonary stenosis, patent ductus arteriosus, and characteristic ECG abnormalities.
Observational (n=21)
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Twenty-one patients with Noonan syndrome are presented. Telecanthus low-set ears, epicanthus and facial asymmetry were the commoner facial stigmata. Pterygium colli, pectus excavatum-carinatum and mild physical and mental retardation were also common features. Pulmonary stenosis and patent ductus arteriosus were the most frequent cardiac anomalies. Wide QRS, left axis deviation, giant Q waves and a negative pattern in V6 were useful electrocardiographic signs. We speculate that the Noonan syndrome could be considered as a branchial arch development syndrome.
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A Sanchezcascos (1983) conducted an observational in Noonan syndrome (n=21). Noonan syndrome was evaluated on Clinical, cardiac, and electrocardiographic features. Noonan syndrome in 21 patients frequently presented with pulmonary stenosis, patent ductus arteriosus, and ECG signs including wide QRS, left axis deviation, giant Q waves, and negative V6.
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